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Research Project Conducted

Research Project in KAIST

2022.Apr
- Present

Research Project Title: Data-Driven Digital Therapeutics (DTx) Analytics Platform Research

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Ministry of Science and ICT; MSIT)

Summary of Research :

Digital therapeutics (DTx), unlike traditional treatments such as pills, uses software installed in smartphones or wearable devices as software as a medical device (SaMD) to cure diseases and improve health conditions, which is a major departure from existing wellness products (e.g., Fitbits). As with traditional therapeutics, DTx also requires clinical validation of efficacy through systematic clinical trials. The US FDA has already authorized a number of DTx products, for example, WellDoc's BlueStar for diabetes management, and Pear Therapeutics' reSET for drug addiction recovery, opening up new DTx possibilities, such as doctors' prescriptions and insurance reimbursement. Unlike traditional drug development, the cost of DTx development is relatively low, and new DTx markets are growing rapidly. The DTx market is estimated to increase to $8.7 billion in 2025, with an average annual growth rate of 20% (GrandView 2017).

DTx therapies mostly consider behavioral changes in chronic diseases (e.g., diabetes and cardiovascular diseases) and neuropsychiatric diseases (e.g., depression, sleep disorders, and ADHD). These are the areas in which the treatment effects of cognitive behavior therapies are significant. DTx therapies can deliver patient-centered care by supplementing the areas in which treatment is difficult or poorly managed through existing treatment methods (e.g., lifestyle coaching and cognitive behavior therapies), to improve the quality of care at lower costs.

One of the important components of traditional drug development is the selection and optimization of a drug delivery system that aims to effectively deliver a specific drug to the desired target (e.g., sustained release with microneedle patches). Digital therapeutics can deliver various interventions through digital technologies (e.g., interactive mobile content, videos, chatbots, and push notifications). Thus, it is very important to analyze and optimize the engagement and receptivity of “DTx delivery systems”' using mobile and wearable devices.

The receptivity to DTx relates to the overall process of intervention delivery using digital devices (e.g., notification delivery, notification perception/checking, and behavioral adherence). DTx aims to induce behavioral changes in users, and it is very important to analyze patient DTx engagement and receptivity to shorten the DTx development time and maximize the effectiveness of DTx. This project aims to investigate user engagement and intervention receptivity to DTx by analyzing digital footprint data (known as digital phenotype data) collected from mobile and wearable devices. Data-driven DTx analytics for user engagement and intervention receptivity in DTx delivery systems will provide key insights for the improvements of DTx, possibly innovating the existing paradigm of DTx development processes

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2022.Apr
- Present

Research Project Title: Development of Human Digital Twin Technologies for Prediction and Management of Emotion Workers' Mental Health Risks

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)

Summary of Research : Development and Empirical research on Interactive Human Digital Twin Technology that provides personalized stress risk management solutions by synchronizing /simulating the operation process of individual stress risk factors in a virtual environment for mental health risk management due to emotional labor.

2021.Feb
- Present

Research Project Title: Mental Health Inference and Intervention with Mobile and Wearable Computing

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)

Goal: Diagnose and track mental health status by extracting
cognitive behavior routines from smartphone interaction data
Problem: The paradigm of mental health
diagnostic technology needs to change
Overall Method:
Development of cognitive behavior computing technology for cognitive ability and mental health status diagnosis and tracking via cognitive behavior routine in daily life using smart devices
1st implementation:
Development of SW construction and data quality assurance technology for cognitive behavior data collection
2nd implementation:
Extraction of cognitive behavior routines and development of cognitive behavior state estimation/tracking models based on routine data
3rd implementation:
Development of routine data collection and multi-routine integrated model-based personalized
diagnosis and tracking indicators

2019. Aug -  
2021. Feb

Research Project Title: Research and Development of Intelligent Interaction Technology that Understands the User's Intention and Context

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)

Design the Overview of Holistic Quantified Self (HQS) Data Collection Platform
Development of Personal Big Data Collection 
Platform by Smart Devices and IoT Sensors
Building Multi-Dimensional Data Integrated Collection Platform with HQS 
Research on Personality, Stress, and Emotional Prediction Model via HQS Data-Driven Analytics

2018. Aug -  
2019. Feb

Research Project Title: Artificial Intelligence Algorithm-based Vascular Intervention Robot System to Reduce Radiation Exposure and Achieve Accuracy of 0.5mm Level

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Ministry of Trade, Industry and Energy; Artificial Intelligence Bio Robot Medical Convergence Project)

Deep Transfer network based Vascular Intervention Robot System Improved Existing System
cycleGAN based Improving Resolution of Actual Surgical Image

Research Project in POSTECH

2016.Jan
- 2018.Apr

Research Project Title: Advancement of a Swallowing Monitoring Device and Analysis Protocols

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government 

Goal: Developing techniques for predicting or early screening of swallowing disorders by quantitatively measuring swallowing ability
Limitations of Existing Swallowing Function Test Equipment:
radiation use, inserting an endoscope into the body 
Solution
Swallowing function monitoring S/W development
Development of swallowing measurement system

2016. Jan -  
2018. Apr

Research Project Title: Development of an Ergonomic Design Methodology for the Shape of Product based on Human-Product Deformation Analysis Models

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government

Anticipatory Effect and Application of Product Design Technology Based on Analysis of Human Product Shape Transformation

2016. Mar -  
2017. Feb

Research Project Title: Development of Seat Motion System for Passive Task-related Fatigue Reduction during Driving and Evaluation of Simulated Driving Verification

 

Sponsor: Corp. Hyundai NGV

Passive Task-Related (TR) Fatigue
Driver fatigue evaluation scale
Experimental evaluation device configuration
In vehicle evaluation environment
Evaluation Results: Subjective Fatigue
Evaluation Result: Subjective Fatigue

2016. May -  
2017. Dec

Research Project Title: Evaluation of Cognitive Function and Development of Cognitive Enhancement Medical Devices for Patient with Cognitive Impairment

 

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Korea Evaluation Institute of Industrial Technology; KEIT)

Cognitive function evaluation and promotion system

2016. Aug -  
2017. July

Research Project Title: Research on KF-X Fighter Plane's MFD/HUD/LAD PVI Design Techniques Considering Ergonomics

 

Sponsor: Corp. Korea Aerospace Industries

2016. Jan -  
2015. May

Research Project Title: Development of a Hip Fracture Prevention Product based on 3D Body Shapes and a Biomechanical Analysis

Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government

Design model and fabrication process
of hip protector testing system
Evaluation of virtual adhesion using
CLO program
Module Configuration of Finite Element Analysis for Impact Performance Visualization Evaluation
Comparison of strain and clothing pattern
(Development HP vs Existing HP)
Hip Protector performance evaluation for hip and skin specimens; Hip protector testing system design model and production process
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