Research Project Conducted
Research Project in KAIST
2022.Apr
- Present
Research Project Title: Data-Driven Digital Therapeutics (DTx) Analytics Platform Research
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Ministry of Science and ICT; MSIT)
Summary of Research :
Digital therapeutics (DTx), unlike traditional treatments such as pills, uses software installed in smartphones or wearable devices as software as a medical device (SaMD) to cure diseases and improve health conditions, which is a major departure from existing wellness products (e.g., Fitbits). As with traditional therapeutics, DTx also requires clinical validation of efficacy through systematic clinical trials. The US FDA has already authorized a number of DTx products, for example, WellDoc's BlueStar for diabetes management, and Pear Therapeutics' reSET for drug addiction recovery, opening up new DTx possibilities, such as doctors' prescriptions and insurance reimbursement. Unlike traditional drug development, the cost of DTx development is relatively low, and new DTx markets are growing rapidly. The DTx market is estimated to increase to $8.7 billion in 2025, with an average annual growth rate of 20% (GrandView 2017).
DTx therapies mostly consider behavioral changes in chronic diseases (e.g., diabetes and cardiovascular diseases) and neuropsychiatric diseases (e.g., depression, sleep disorders, and ADHD). These are the areas in which the treatment effects of cognitive behavior therapies are significant. DTx therapies can deliver patient-centered care by supplementing the areas in which treatment is difficult or poorly managed through existing treatment methods (e.g., lifestyle coaching and cognitive behavior therapies), to improve the quality of care at lower costs.
One of the important components of traditional drug development is the selection and optimization of a drug delivery system that aims to effectively deliver a specific drug to the desired target (e.g., sustained release with microneedle patches). Digital therapeutics can deliver various interventions through digital technologies (e.g., interactive mobile content, videos, chatbots, and push notifications). Thus, it is very important to analyze and optimize the engagement and receptivity of “DTx delivery systems”' using mobile and wearable devices.
The receptivity to DTx relates to the overall process of intervention delivery using digital devices (e.g., notification delivery, notification perception/checking, and behavioral adherence). DTx aims to induce behavioral changes in users, and it is very important to analyze patient DTx engagement and receptivity to shorten the DTx development time and maximize the effectiveness of DTx. This project aims to investigate user engagement and intervention receptivity to DTx by analyzing digital footprint data (known as digital phenotype data) collected from mobile and wearable devices. Data-driven DTx analytics for user engagement and intervention receptivity in DTx delivery systems will provide key insights for the improvements of DTx, possibly innovating the existing paradigm of DTx development processes
2022.Apr
- Present
Research Project Title: Development of Human Digital Twin Technologies for Prediction and Management of Emotion Workers' Mental Health Risks
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)
Summary of Research : Development and Empirical research on Interactive Human Digital Twin Technology that provides personalized stress risk management solutions by synchronizing /simulating the operation process of individual stress risk factors in a virtual environment for mental health risk management due to emotional labor.
2021.Feb
- Present
Research Project Title: Mental Health Inference and Intervention with Mobile and Wearable Computing
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)
Goal: Diagnose and track mental health status by extracting
cognitive behavior routines from smartphone interaction data
Problem: The paradigm of mental health
diagnostic technology needs to change
Overall Method:
Development of cognitive behavior computing technology for cognitive ability and mental health status diagnosis and tracking via cognitive behavior routine in daily life using smart devices
1st implementation:
Development of SW construction and data quality assurance technology for cognitive behavior data collection
2nd implementation:
Extraction of cognitive behavior routines and development of cognitive behavior state estimation/tracking models based on routine data
3rd implementation:
Development of routine data collection and multi-routine integrated model-based personalized
diagnosis and tracking indicators
2019. Aug -
2021. Feb
Research Project Title: Research and Development of Intelligent Interaction Technology that Understands the User's Intention and Context
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science and ICT; MSIT)
Design the Overview of Holistic Quantified Self (HQS) Data Collection Platform
Development of Personal Big Data Collection
Platform by Smart Devices and IoT Sensors
Building Multi-Dimensional Data Integrated Collection Platform with HQS
Research on Personality, Stress, and Emotional Prediction Model via HQS Data-Driven Analytics
2018. Aug -
2019. Feb
Research Project Title: Artificial Intelligence Algorithm-based Vascular Intervention Robot System to Reduce Radiation Exposure and Achieve Accuracy of 0.5mm Level
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Ministry of Trade, Industry and Energy; Artificial Intelligence Bio Robot Medical Convergence Project)
Deep Transfer network based Vascular Intervention Robot System Improved Existing System
cycleGAN based Improving Resolution of Actual Surgical Image
Research Project in POSTECH
2016.Jan
- 2018.Apr
Research Project Title: Advancement of a Swallowing Monitoring Device and Analysis Protocols
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government
Goal: Developing techniques for predicting or early screening of swallowing disorders by quantitatively measuring swallowing ability
Limitations of Existing Swallowing Function Test Equipment:
radiation use, inserting an endoscope into the body
Solution
Swallowing function monitoring S/W development
Development of swallowing measurement system
2016. Jan -
2018. Apr
Research Project Title: Development of an Ergonomic Design Methodology for the Shape of Product based on Human-Product Deformation Analysis Models
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government
Anticipatory Effect and Application of Product Design Technology Based on Analysis of Human Product Shape Transformation
2016. Mar -
2017. Feb
Research Project Title: Development of Seat Motion System for Passive Task-related Fatigue Reduction during Driving and Evaluation of Simulated Driving Verification
Sponsor: Corp. Hyundai NGV
Passive Task-Related (TR) Fatigue
Driver fatigue evaluation scale
Experimental evaluation device configuration
In vehicle evaluation environment
Evaluation Results: Subjective Fatigue
Evaluation Result: Subjective Fatigue
2016. May -
2017. Dec
Research Project Title: Evaluation of Cognitive Function and Development of Cognitive Enhancement Medical Devices for Patient with Cognitive Impairment
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (Korea Evaluation Institute of Industrial Technology; KEIT)
Cognitive function evaluation and promotion system
2016. Aug -
2017. July
Research Project Title: Research on KF-X Fighter Plane's MFD/HUD/LAD PVI Design Techniques Considering Ergonomics
Sponsor: Corp. Korea Aerospace Industries
2016. Jan -
2015. May
Research Project Title: Development of a Hip Fracture Prevention Product based on 3D Body Shapes and a Biomechanical Analysis
Sponsor: This work has been supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government
Design model and fabrication process
of hip protector testing system
Evaluation of virtual adhesion using
CLO program
Module Configuration of Finite Element Analysis for Impact Performance Visualization Evaluation
Comparison of strain and clothing pattern
(Development HP vs Existing HP)
